Article
Individual QTLs controlling quantitative variation in blood pressure inherited in a Mendelian mode.
Heredity - 1 Mar 2007
Duong C, Charron S, Deng Y, Xiao C, Ménard A, Roy J, Deng A Y
Abstract excerpt
We studied three possible genotypes at 10 well-defined blood pressure (BP) QTLs using congenic rat lines. The central question was whether the hypertensive or normotensive allele is dominant, or whether there is partial dominance. The congenic strains were employed to investigate the BP effects of alleles originating from normotensive rats in the background of hypertensive Dahl salt-sensitive (DSS) rats. The...
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