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Article

Protein expression and gene amplification of epidermal growth factor receptor in thymomas

3 Jan 2005

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR) overexpression and amplification are important prognostic factors in many solid tumors and anti-EGFR antibody-based therapy is now available as a promising therapeutic modality. There is little information in the literature regarding the biologic role of EGFR in thymomas that are characterized by variable clinical presentations, histologic heterogeneity, and...

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PMID: 15630697
DOI: 10.1002/cncr.20811

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