Article
The role of histone H2Av variant replacement and histone H4 acetylation in the establishment of Drosophila heterochromatin.
Genes & development - 1 Jan 2005
Swaminathan Jyothishmathi, Baxter Ellen M, Corces Victor G
Abstract excerpt
Activation and repression of transcription in eukaryotes involve changes in the chromatin fiber that can be accomplished by covalent modification of the histone tails or the replacement of the canonical histones with other variants. Here we show that the histone H2A variant of Drosophila melanogaster, H2Av, localizes to the centromeric heterochromatin, and it is recruited to an ectopic heterochromatin site formed...
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