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Article

Human Fetal Mesenchymal Stem Cells as Vehicles for Gene Delivery

1 Jan 2005

Abstract excerpt

First-trimester fetal blood contains a readily expandable population of stem cells, human fetal mesenchymal stem cells (hfMSCs), which might be exploited for autologous intrauterine gene therapy. We investigated the self-renewal and differentiation of hfMSCs after transduction with onco-retroviral and lentiviral vectors. After transduction with either a MoMuLV retrovirus or an HIV-1-based lentiviral vector...

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Identifiers

PMID: 15625126
DOI: 10.1634/stemcells.2004-0138

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