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Non-viral gene delivery to human mesenchymal stem cells: a practical guide towards cell engineering

25 Jul 2023

Abstract excerpt

In recent decades, human mesenchymal stem cells (hMSCs) have gained momentum in the field of cell therapy for treating cartilage and bone injuries. Despite the tri-lineage multipotency, proliferative properties, and potent immunomodulatory effects of hMSCs, their clinical potential is hindered by donor variations, limiting their use in medical settings. To address this challenge, gene delivery technologies have...

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PMID: 37491322
DOI: 10.1186/s13036-023-00363-7

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