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Adeno-associated viral vector transduction of human mesenchymal stem cells

31 May 2007

Abstract excerpt

Mesenchymal stem cells (MSCs) have received considerable attention in the emerging field of regenerative medicine. One aspect of MSC research focuses on genetically modifying the cells with the aim of enhancing their regenerative potential. Adeno-associated virus (AAV) holds promise as a vector for human gene therapy, primarily due to its lack of pathogenicity and low risk of insertional mutagenesis. However, the...

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PMID: 17538898
DOI: 10.22203/ecm.v013a10

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