Article
Molecular cloning and expression of hepatitis C virus core protein and production of monoclonal antibodies to the recombinant protein.
Asian Pacific journal of allergy and immunology - 1 Jun 1996
Songsivilai S, Dharakul T, Kunkitti R, Thepthai C
Abstract excerpt
The gene encoding nucleocapsid (core) protein of hepatitis C virus (HCV) was isolated from a Thai blood donor infected with HCV genotype 1b. The nucleotide sequence of this clone showed a high degree of homology to that of 4 HCV strains isolated from other Thai blood donors as well as that of the HCV prototypes of genotypes 1a, 1b, 2a and 3a. The entire region of the core gene was cloned into an expression...
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