Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring the genetics of longevity in the Old Order Amish.

Mechanisms of ageing and development - 1 Feb 2005

Sorkin John, Post Wendy, Pollin Toni I, O'Connell Jeffrey R, Mitchell Braxton D, Shuldiner Alan R

Abstract excerpt

Lifespan is a complex phenotype determined by the interaction of genetic and environmental factors. This makes the identification of variants in genes that influence longevity challenging. We believe that the Old Order Amish (OOA) of Lancaster, Pennsylvania is an excellent population for studying the genetics of longevity. They are a closed population derived from a limited number of founders. They have large...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to DNA, Mitochondrial
Share to Environment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Founder Effect

Share to Genetics, Population

Share to Longevity

Share to Pennsylvania

Share to Rural Population

Source

Identifiers

PMID: 15621217
DOI: 10.1016/j.mad.2004.08.027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring the genetics of longevity in the Old Order Amish.PMID 15621217Read ↗

Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish.Semantic proximity Read ↗

Extent and distribution of linkage disequilibrium in the Old Order Amish.Semantic proximity Read ↗

Genetics of Human Longevity Within an Eco-Evolutionary Nature-Nurture FrameworkSemantic proximity Read ↗

Centenarians as extreme phenotypes: An ecological perspective to get insight into the relationship between the genetics of longevity and age-associated diseases.Semantic proximity Read ↗

The genetic architecture of Alzheimer disease risk in the Ohio and Indiana AmishSemantic proximity Read ↗

The genetics of exceptional human longevity.Semantic proximity Read ↗

Investigations of the Y chromosome, male founder structure and YSTR mutation rates in the Old Order Amish.Semantic proximity Read ↗

The genetics of exceptional human longevity.Semantic proximity Read ↗

The unusual genetics of human longevity.Semantic proximity Read ↗

Four Genome-Wide Association Studies Identify New Extreme Longevity Variants.Semantic proximity Read ↗

The genetics of exceptional longevity: Insights from centenarians.Semantic proximity Read ↗

Examination of candidate exonic variants for association to Alzheimer disease in the Amish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.