The unusual genetics of human longevity.

doi:10.1126/sageke.2006.10.pe20

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Article

The unusual genetics of human longevity.

Science of aging knowledge environment : SAGE KE - 28 Jun 2006

De Benedictis Giovanna, Franceschi Claudio

Abstract excerpt

In no species other than humans do cultural, social, and biological factors interact with each other in modulating complex phenotypes. Thus, the identification of genetic factors that affect human longevity is a true challenge. The model of centenarians provides us a unique opportunity to tackle this challenge. In this Perspective, we discuss some recent findings (the impact of geography and demography on the...

Topics

Demography
Genetic Predisposition to Disease
Genotype
Geography
Longevity
Humans

Source

Open in PubMed

Identifiers

PMID: 16807484
DOI: 10.1126/sageke.2006.10.pe20

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