Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamics of GBF1, a Brefeldin A-sensitive Arf1 exchange factor at the Golgi.

Molecular biology of the cell - 1 Mar 2005

Niu Ting-Kuang, Pfeifer Andrea C, Lippincott-Schwartz Jennifer, Jackson Catherine L

Abstract excerpt

Trafficking through the Golgi apparatus requires members of the Arf family of GTPases, whose activation is regulated by guanine nucleotide exchange factors (GEFs). Once activated, Arf-GTP recruits effectors such as coat complexes and lipid-modifying enzymes to specific membrane sites, creating a domain competent for cargo concentration and transport. GBF1 is a peripherally associated Arf GEF involved in both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP-Ribosylation Factor 1
Share to Brefeldin A
Share to Golgi Apparatus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Guanine Nucleotide Exchange Factors

Share to Guanosine Triphosphate

Share to Image Processing, Computer-Assisted

Share to Luminescent Proteins

Share to Spectrometry, Fluorescence

Source

Open in PubMed Open full text

Identifiers

PMID: 15616190
DOI: 10.1091/mbc.e04-07-0599
PMCID: PMC551486

Genes

GBF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamics of GBF1, a Brefeldin A-sensitive Arf1 exchange factor at the Golgi.PMID 15616190Read ↗

Dissection of membrane dynamics of the ARF-guanine nucleotide exchange factor GBF1.Semantic proximity Read ↗

Characterization of class I and II ADP-ribosylation factors (Arfs) in live cells: GDP-bound class II Arfs associate with the ER-Golgi intermediate compartment independently of GBF1.Semantic proximity Read ↗

Highly conserved motifs within the large Sec7 ARF guanine nucleotide exchange factor GBF1 target it to the Golgi and are critical for GBF1 activity.Semantic proximity Read ↗

An ARF-GEF acting at the Golgi and in selective endocytosis in polarized plant cells.Semantic proximity Read ↗

A critical role of a cellular membrane traffic protein in poliovirus RNA replication.Semantic proximity Read ↗

BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: its localization to recycling endosomes and implication in the endosome integrity.Semantic proximity Read ↗

Identification of GBF1 as a Cellular Factor Required for Hepatitis C Virus RNA ReplicationSemantic proximity Read ↗

COPI recruitment is modulated by a Rab1b-dependent mechanism.Semantic proximity Read ↗

Dual specificity of the interfacial inhibitor brefeldin a for arf proteins and sec7 domains.Semantic proximity Read ↗

In vivo monitoring of the recruitment and activation of AP-1 by Arf1.Semantic proximity Read ↗

A novel small molecule regulator of guanine nucleotide exchange activity of the ADP-ribosylation factor and golgi membrane trafficking.Semantic proximity Read ↗

Arf1 dissociates from the clathrin adaptor GGA prior to being inactivated by Arf GTPase-activating proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.