Article
Arf1 dissociates from the clathrin adaptor GGA prior to being inactivated by Arf GTPase-activating proteins.
The Journal of biological chemistry - 6 Dec 2002
Jacques Kerry M, Nie Zhongzhen, Stauffer Stacey, Hirsch Dianne S, Chen Ling-Xin, Stanley Katherine T, Randazzo Paul A
Abstract excerpt
The effectors of monomeric GTP-binding proteins can influence interactions with GTPase-activating proteins (GAPs) in two ways. In one case, effector and GAP binding to the GTP-binding protein is mutually exclusive. In another case, the GTP-binding protein bound to an effector is the substrate for the GTPase-activating protein. Here predictions for these two mechanisms were tested for the Arf1 effector GGA and...
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