Article
Characterization of class I and II ADP-ribosylation factors (Arfs) in live cells: GDP-bound class II Arfs associate with the ER-Golgi intermediate compartment independently of GBF1.
Molecular biology of the cell - 1 Aug 2008
Chun Justin, Shapovalova Zoya, Dejgaard Selma Y, Presley John F, Melançon Paul
Abstract excerpt
Despite extensive work on ADP-ribosylation factor (Arf) 1 at the Golgi complex, the functions of Arf2-5 in the secretory pathway, or for that of any Arf at the ER-Golgi intermediate compartment (ERGIC) remain uncharacterized. Here, we examined the recruitment of fluorescently tagged Arf1, -3, -4,...
Topics
- ADP-Ribosylation Factors
- Adenosine Diphosphate
- Animals
- Binding Sites
- Brefeldin A
- COS Cells
- Chlorocebus aethiops
- Endoplasmic Reticulum
- Golgi Apparatus
- Guanine Nucleotide Exchange Factors
- Guanosine Diphosphate