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Article

Imprinting and looping: epigenetic marks control interactions between regulatory elements.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jan 2005

Kato Yuzuru, Sasaki Hiroyuki

Abstract excerpt

Gene regulation involves various cis-regulatory elements that can act at a distance. They may physically interact each other or with their target genes to exert their effects. Such interactions are beginning to be uncovered in the imprinted Igf2/H19 domain.(1) The differentially methylated region...

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Identifiers

PMID: 15612042
DOI: 10.1002/bies.20171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15612042-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Imprinting and looping: epigenetic marks control interactions between regulatory elements.PMID 15612042Read ↗

Mechanisms of Igf2/H19 Imprinting: DNA Methylation, Chromatin and Long-Distance Gene RegulationSemantic proximity Read ↗

Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loopsSemantic proximity Read ↗

Genomic imprinting controls matrix attachment regions in the Igf2 gene.Semantic proximity Read ↗

A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal Igf2 allele.Semantic proximity Read ↗

The human and mouse H19 imprinting control regions harbor an evolutionarily conserved silencer element that functions on transgenes in Drosophila.Semantic proximity Read ↗

CTCF binding at the <i>H19</i> imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to <i>Igf2</i>Semantic proximity Read ↗

H19 lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1.Semantic proximity Read ↗

Epigenetic regulation of the <i>Igf2/H19</i> gene clusterSemantic proximity Read ↗

The imprinting box of the mouse Igf2r gene.Semantic proximity Read ↗

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 geneSemantic proximity Read ↗

Tissue-specific insulator function at H19/Igf2 revealed by deletions at the imprinting control region.Semantic proximity Read ↗

Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactionsSemantic proximity Read ↗

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