Article
Genomic imprinting controls matrix attachment regions in the Igf2 gene.
Molecular and cellular biology - 1 Dec 2003
Weber Michaël, Hagège Hélène, Murrell Adele, Brunel Claude, Reik Wolf, Cathala Guy, Forné Thierry
Abstract excerpt
Genomic imprinting at the Igf2/H19 locus originates from allele-specific DNA methylation, which modifies the affinity of some proteins for their target sequences. Here, we show that AT-rich DNA sequences located in the vicinity of previously characterized differentially methylated regions (DMRs)...
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