Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic imprinting controls matrix attachment regions in the Igf2 gene.

Molecular and cellular biology - 1 Dec 2003

Weber Michaël, Hagège Hélène, Murrell Adele, Brunel Claude, Reik Wolf, Cathala Guy, Forné Thierry

Abstract excerpt

Genomic imprinting at the Igf2/H19 locus originates from allele-specific DNA methylation, which modifies the affinity of some proteins for their target sequences. Here, we show that AT-rich DNA sequences located in the vicinity of previously characterized differentially methylated regions (DMRs) of the imprinted Igf2 gene are conserved between mouse and human. These sequences have all the characteristics of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Composition
Share to DNA Methylation
Share to Genomic Imprinting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor II

Share to Mice, Inbred CBA

Share to RNA, Long Noncoding

Share to RNA, Untranslated

Share to Tissue Distribution

Source

Open in PubMed Open full text

Identifiers

PMID: 14645508
DOI: 10.1128/MCB.23.24.8953-8959.2003
PMCID: PMC309645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic imprinting controls matrix attachment regions in the Igf2 gene.PMID 14645508Read ↗

Extensive tissue-specific variation of allelic methylation in the Igf2 gene during mouse fetal development: relation to expression and imprinting.Semantic proximity Read ↗

The imprinting box of the mouse Igf2r gene.Semantic proximity Read ↗

IGF2: epigenetic regulation and role in development and disease.Semantic proximity Read ↗

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signalSemantic proximity Read ↗

Imprinting and looping: epigenetic marks control interactions between regulatory elements.Semantic proximity Read ↗

An intragenic methylated region in the imprinted Igf2 gene augments transcription.Semantic proximity Read ↗

The histone code regulating expression of the imprinted mouse Igf2r gene.Semantic proximity Read ↗

CTCF binding at the <i>H19</i> imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to <i>Igf2</i>Semantic proximity Read ↗

The human and mouse H19 imprinting control regions harbor an evolutionarily conserved silencer element that functions on transgenes in Drosophila.Semantic proximity Read ↗

H19 lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1.Semantic proximity Read ↗

Mechanisms of Igf2/H19 Imprinting: DNA Methylation, Chromatin and Long-Distance Gene RegulationSemantic proximity Read ↗

The landscape of genomic imprinting across diverse adult human tissues.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.