Article
Cell size and Cln-Cdc28 complexes mediate entry into meiosis by modulating cell growth.
Cell cycle (Georgetown, Tex.) - 1 Nov 2004
Day Audra, Markwardt Jody, Delaguila Rolando, Zhang Jian, Purnapatre Kedar, Honigberg Saul M, Schneider Brandt L
Abstract excerpt
In the yeast Saccharomyces cerevisiae, mitotic cell cycle progression depends upon the G(1)-phase cyclin-dependent kinase Cln-Cdc28 and cell growth to a minimum cell size. In contrast, Cln-Cdc28 inhibits entry into meiosis, and a cell growth requirement for sporulation has not been established. Here, we report that entry into meiosis also depends upon cell growth. Moreover, sporulation and cell growth rates were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.