Article
The G(1) cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6.
Molecular and cellular biology - 1 Jun 2002
Wijnen Herman, Landman Allison, Futcher Bruce
Abstract excerpt
In Saccharomyces cerevisiae (budding yeast), commitment to cell division in late G(1) is promoted by the G(1) cyclin Cln3 and its associated cyclin-dependent kinase, Cdc28. We show here that all known aspects of the function of Cln3 in G(1) phase, including control of cell size, pheromone sensitivity, cell cycle progress, and transcription, require the protein Swi6. Swi6 is a component of two related...
Topics
- CDC28 Protein Kinase, S cerevisiae
- Cell Cycle
- Cyclins
- DNA-Binding Proteins
- Fungal Proteins
- G1 Phase
- Mutation
- Pheromones
- Phosphorylation
- Saccharomyces cerevisiae Proteins
- Transcription Factors
- Transcription, Genetic
- Yeasts