Article
Aldosteronism and a proinflammatory vascular phenotype: role of Mg2+, Ca2+, and H2O2 in peripheral blood mononuclear cells.
Circulation - 4 Jan 2005
Ahokas Robert A, Sun Yao, Bhattacharya Syamal K, Gerling Ivan C, Weber Karl T
Abstract excerpt
BACKGROUND: Chronic, inappropriate (relative to dietary Na+) elevations in circulating aldosterone, such as occur in congestive heart failure, are accompanied by a proinflammatory vascular phenotype involving the coronary and systemic vasculature. An immunostimulatory state with activated periphe...
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