Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High frequency of somatic mitochondrial DNA mutations in human thyroid carcinomas and complex I respiratory defect in thyroid cancer cell lines.

Oncogene - 17 Feb 2005

Abu-Amero Khaled K, Alzahrani Ali S, Zou Minjing, Shi Yufei

Abstract excerpt

Significant progress has been made to elucidate the molecular mechanisms that determine thyroid tumor development and progression. However, most investigations have mainly focused on the genetic alterations of nuclear DNA. The potential role of mitochondrial DNA (mtDNA) mutations in thyroid tumorigenesis is not well defined. In the present study, we investigated the frequency of mtDNA mutations in 24 thyroid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to Cell Line, Tumor
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electron Transport Complex I

Share to Mitochondrial Function and Pathology

Share to Mutation

Share to Neoplasm Staging

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 15608681
DOI: 10.1038/sj.onc.1208292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High frequency of somatic mitochondrial DNA mutations in human thyroid carcinomas and complex I respiratory defect in thyroid cancer cell lines.PMID 15608681Read ↗

Thyroid Cancer-Associated Mitochondrial DNA Mutation G3842A Promotes Tumorigenicity via ROS-Mediated ERK1/2 Activation.Semantic proximity Read ↗

Analysis of mitochondrial DNA mutations in D-loop region in thyroid lesions.Semantic proximity Read ↗

A Comprehensive Characterization of Mitochondrial Genome in Papillary Thyroid Cancer.Semantic proximity Read ↗

The Mitochondrial DNA Control Region might have useful Diagnostic and Prognostic Biomarkers for Thyroid TumorsSemantic proximity Read ↗

Mitochondrial DNA and human thyroid diseases.Semantic proximity Read ↗

Mitochondrial DNA alterations in thyroid cancer.Semantic proximity Read ↗

Mitochondrial D-Loop instability in thyroid tumours is not a marker of malignancy.Semantic proximity Read ↗

Association of mitochondrial DNA transversion mutations with familial medullary thyroid carcinoma/multiple endocrine neoplasia type 2 syndrome.Semantic proximity Read ↗

[Somatic mutations of mitochondrial DNA in thyroid papillary carcinoma].Semantic proximity Read ↗

Mitochondrial DNA copy number and risk of papillary thyroid carcinomaSemantic proximity Read ↗

Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors.Semantic proximity Read ↗

Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.