Article
In vitro antibacterial activities of new fluoroquinolones against clinical isolates of haemophilus influenzae with ciprofloxacin-resistance-associated alterations in GyrA and ParC.
Chemotherapy - 1 Dec 2004
Yoshizumi Satoshi, Takahashi Yoshie, Watanabe Yoshinari, Okezaki Eiichi, Ishii Yoshikazu, Tateda Kazuhiro
Abstract excerpt
BACKGROUND: The in vitro antimicrobial activities of new fluoroquinolones were tested against quinolone-resistant Haemophilus influenzae of clinical isolates. METHODS: The nucleotide sequences of the gyrA and parC genes from three ciprofloxacin-resistant strains of Haemophilus influenzae (MIC, 1.56-6.25 microg/ml) were determined. The gyrase was purified from the clinical isolates, and the inhibitory activities...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.