Article
Study of isolation of fluoroquinolone-resistant Ureaplasma urealyticum and identification of mutant sites.
Chinese medical journal - 1 Oct 2002
Zhang Wenbo, Wu Yimou, Yin Weiguo, Yu Minjun
Abstract excerpt
OBJECTIVE: To study the resistance mechanism of clinical isolates of Ureaplasma urealyticum resistant to fluoroquinolones. METHODS: Thirteen isolates of Ureaplasma urealyticum resistant to six fluoroquinolones were selected out of 184 clinical isolates and their QRDRs (quinolone resistance-determining region) gyrA, gyrB, parC and parE were amplified by PCR. Sequencing results were compared to those susceptible...
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