Study of isolation of fluoroquinolone-resistant Ureaplasma urealyticum and identification of mutant sites.

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Article

Study of isolation of fluoroquinolone-resistant Ureaplasma urealyticum and identification of mutant sites.

Chinese medical journal - 1 Oct 2002

Zhang Wenbo, Wu Yimou, Yin Weiguo, Yu Minjun

Abstract excerpt

OBJECTIVE: To study the resistance mechanism of clinical isolates of Ureaplasma urealyticum resistant to fluoroquinolones. METHODS: Thirteen isolates of Ureaplasma urealyticum resistant to six fluoroquinolones were selected out of 184 clinical isolates and their QRDRs (quinolone resistance-determining region) gyrA, gyrB, parC and parE were amplified by PCR. Sequencing results were compared to those susceptible...

Topics

Amino Acid Substitution
Anti-Infective Agents
DNA Gyrase
DNA Topoisomerase IV
Drug Resistance, Multiple, Bacterial
Fluoroquinolones
Humans
Mutation
Polymerase Chain Reaction
Ureaplasma urealyticum

Source

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Identifiers

PMID: 12490114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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