Molecular characterization of fluoroquinolones, macrolides, and imipenem resistance in Haemophilus influenzae: analysis of the mutations in QRDRs and assessment of the extent of the AcrAB-TolC-mediated resistance.

doi:10.1007/s10096-018-3362-z

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Article

Molecular characterization of fluoroquinolones, macrolides, and imipenem resistance in Haemophilus influenzae: analysis of the mutations in QRDRs and assessment of the extent of the AcrAB-TolC-mediated resistance.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Nov 2018

Cherkaoui Abdessalam, Gaïa Nadia, Baud Damien, Leo Stefano, Fischer Adrien, Ruppe Etienne, François Patrice, Schrenzel Jacques

Abstract excerpt

The aims of the present study were to characterize the mechanisms of resistance to fluoroquinolones, macrolides, and imipenem in Haemophilus influenzae, to assess the extent of the AcrAB-TolC-mediated resistance, and to define a core genome multilocus sequence typing (cgMLST) scheme for H. influe...

Topics

Adult
Aged
Anti-Bacterial Agents
Bacterial Proteins
Female
Fluoroquinolones
Genome, Bacterial
Genomics
Haemophilus Infections
Haemophilus influenzae
Humans
Imipenem
Macrolides

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Microbial Sensitivity Tests

Middle Aged

Multilocus Sequence Typing

Mutation

Source

Open in PubMed

Identifiers

PMID: 30145620
DOI: 10.1007/s10096-018-3362-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-30145620-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.