Article
Ciprofloxacin-resistant Haemophilus influenzae strains possess mutations in analogous positions of GyrA and ParC.
Antimicrobial agents and chemotherapy - 1 Jul 1996
Georgiou M, Muñoz R, Román F, Cantón R, Gómez-Lus R, Campos J, De La Campa A G
Abstract excerpt
The nucleotide sequences of the quinolone resistance-determining regions of the gyrA and parC genes from five ciprofloxacin-resistant strains of Haemophilus influenzae (MICs, 2 to 32 micrograms/ml) isolated from patients with cystic fibrosis and three ciprofloxacin-susceptible strains of H. influ...
Topics
- Amino Acid Sequence
- Anti-Infective Agents
- Base Sequence
- Ciprofloxacin
- DNA Topoisomerases, Type II
- Drug Resistance, Microbial
- Genes, Bacterial
- Haemophilus influenzae
- Molecular Sequence Data
- Mutation
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid
- Transformation, Genetic