Molecular characterization of fluoroquinolone resistance in nontypeable Haemophilus influenzae clinical isolates.

doi:10.1128/AAC.04005-14

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Article

Molecular characterization of fluoroquinolone resistance in nontypeable Haemophilus influenzae clinical isolates.

Antimicrobial agents and chemotherapy - 1 Jan 2015

Puig Carmen, Tirado-Vélez José Manuel, Calatayud Laura, Tubau Fe, Garmendia Junkal, Ardanuy Carmen, Marti Sara, de la Campa Adela G, Liñares Josefina

Abstract excerpt

Nontypeable Haemophilus influenzae (NTHi) is a common cause of respiratory infections in adults, who are frequently treated with fluoroquinolones. The aims of this study were to characterize the genotypes of fluoroquinolone-resistant NTHi isolates and their mechanisms of resistance. Among 7,267 H...

Topics

Aged
Aged, 80 and over
Anti-Bacterial Agents
Bacterial Typing Techniques
Base Sequence
Ciprofloxacin
DNA Gyrase
DNA Topoisomerase IV
DNA, Bacterial
Drug Resistance, Bacterial
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fluoroquinolones

Genetic Variation

Haemophilus Infections

Haemophilus influenzae

Humans

Levofloxacin

Male

Source

Open in PubMed Open full text

Identifiers

PMID: 25385097
DOI: 10.1128/AAC.04005-14
PMCID: PMC4291387

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-25385097-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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