Article
Mitonuclear interactions influence multiple sclerosis risk.
Gene - 20 Oct 2020
Kozin Maxim, Kulakova Olga, Kiselev Ivan, Baulina Natalia, Boyko Alexey, Favorova Olga
Abstract excerpt
Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by the autoimmune inflammation, demyelination, and neurodegeneration. This complex disease develops in genetically predisposed individuals under adverse environmental factors. To date, a large number of MS-associated polymorphic loci of the nuclear genome have been identified; however, their total variability can explain only...
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