Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians.

Journal of the neurological sciences - 15 Jun 2011

Orton Sarah-Michelle, Ramagopalan Sreeram V, Para Andrea E, Lincoln Mathew R, Handunnetthi Lahiru, Chao Michael J, Morahan Julia, Morrison Katie M, Sadovnick A Dessa, Ebers George C

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is determined by interactions between genes and environment and the influence of vitamin D adequacy has been proposed. Previous studies have shown that serum 25-hydroxyvitamin D (25(OH)D) levels are genetically influenced. Polymorphisms in vitamin D pathway genes are candidates for association with MS susceptibility. METHODS: MS patients (n=1364) and their unaffected...

Topics

Join the communities discussing this publication.

25-Hydroxyvitamin D3 1-alpha-Hydroxylase
Canada
Receptors, Calcitriol
Steroid Hydroxylases
Vitamin D

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vitamin D-Binding Protein

Vitamin D Deficiency

Vitamin D3 24-Hydroxylase

Source

Identifiers

PMID: 21440908
DOI: 10.1016/j.jns.2011.02.032

Genes

VDR
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians.PMID 21440908Read ↗

Vitamin D and Genetic Susceptibility to Multiple Sclerosis.Semantic proximity Read ↗

Polymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis.Semantic proximity Read ↗

Exonic variants of genes related to the vitamin D signaling pathway in the families of familial multiple sclerosis using whole‐exome next generation sequencingSemantic proximity Read ↗

Genetic aspects of vitamin D receptor and metabolism in relation to the risk of multiple sclerosis.Semantic proximity Read ↗

Genetic analysis of vitamin D related genes in Canadian multiple sclerosis patients. Canadian Collaborative Study Group.Semantic proximity Read ↗

Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis.Semantic proximity Read ↗

Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis.Semantic proximity Read ↗

Role of gene polymorphisms in vitamin D metabolism and in multiple sclerosis.Semantic proximity Read ↗

FokI vitamin D receptor gene polymorphism in association with multiple sclerosis risk and disability progression in Slovaks.Semantic proximity Read ↗

Association of Vitamin D Metabolism Gene Polymorphisms with Autoimmunity: Evidence in Population Genetic Studies.Semantic proximity Read ↗

Association between 25(OH) vitamin D and multiple sclerosis: cohort, shared genetics, and Causality.Semantic proximity Read ↗

Association of Vitamin D Receptor Gene Polymorphisms and the Risk of Multiple Sclerosis: A Meta Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.