Article
Biological assessment of aspirin efficacy on healthy individuals: heterogeneous response or aspirin failure?
Stroke - 1 Feb 2005
Gonzalez-Conejero Rocio, Rivera Jose, Corral Javier, Acuña Carmen, Guerrero Jose A, Vicente Vincente
Abstract excerpt
BACKGROUND AND PURPOSE: The widespread use of aspirin requires clarification of the aspirin resistance phenomenon. Most studies on this field are focused on patients which may affect the action of aspirin. METHODS: We evaluated the biological efficacy of aspirin in healthy subjects. RESULTS: Agonist-induced platelet aggregation was fully abrogated by 100 mg of aspirin in all individuals. By contrast, with the...
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