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Article

Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin.

Thrombosis and haemostasis - 1 Apr 2009

Pettinella Caterina, Romano Mario, Stuppia Liborio, Santilli Francesca, Liani Rossella, Davì Giovanni

Abstract excerpt

COX-1 polymorphism C50T, in complete linkage disequilibrium with the other polymorphism A-842G, has been depicted as a determinant of pharmacological response to aspirin treatment. Whether these polymorphisms exert an effect on response to aspirin both in vitro and ex vivo is still controversial. We genotyped a population of 148 healthy individuals for the C50T/A-842G haplotype. Thirty of them underwent low-dose...

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PMID: 19350112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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