Article
The emergent phenomenon of aspirin resistance: insights from genetic association studies.
Pharmacogenomics - 1 Jan 2020
Ferreira Márcia, Freitas-Silva Margarida, Assis Joana, Pinto Ricardo, Nunes José P, Medeiros Rui
Abstract excerpt
Despite the clinical benefits of aspirin, the interindividual variation in response to this antiplatelet drug is considerable. The manifestation of aspirin resistance (AR) is frequently observed, although this complex process remains poorly understood. While AR etiology is likely to be multifactorial, genetic factors appear to be preponderant. According to several genetic association studies, both genome-wide and...
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