Article
Analysis of superfamily specific profile-profile recognition accuracy.
BMC bioinformatics - 16 Dec 2004
Casbon James A, Saqi Mansoor A S
Abstract excerpt
BACKGROUND: Annotation of sequences that share little similarity to sequences of known function remains a major obstacle in genome annotation. Some of the best methods of detecting remote relationships between protein sequences are based on matching sequence profiles. We analyse the superfamily specific performance of sequence profile-profile matching. Our benchmark consists of a set of 16 protein superfamilies...
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