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Article

Secondary structure-based profiles: use of structure-conserving scoring tables in searching protein sequence databases for structural similarities.

Proteins - 1 Jan 1991

Lüthy R, McLachlan A D, Eisenberg D

Abstract excerpt

The profile method, for detecting distantly related proteins by sequence comparison, has been extended to incorporate secondary structure information from known X-ray structures. The sequence of a known structure is aligned to sequences of other members of a given folding class. From the known structure, the secondary structure (alpha-helix, beta-strand or "other") is assigned to each position of the aligned...

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Identifiers

PMID: 1881879
DOI: 10.1002/prot.340100307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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