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Article

Prediction of function divergence in protein families using the substitution rate variation parameter alpha.

Molecular biology and evolution - 1 Jul 2006

Abhiman Saraswathi, Daub Carsten O, Sonnhammer Erik L L

Abstract excerpt

Protein families typically embody a range of related functions and may thus be decomposed into subfamilies with, for example, distinct substrate specificities. Detection of functionally divergent subfamilies is possible by methods for recognizing branches of adaptive evolution in a gene tree. As...

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PMID: 16672285
DOI: 10.1093/molbev/msl002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16672285-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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