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Article

Mosaic eyes, genomic instability mutants, and cancer susceptibility.

Methods in cell biology - 1 Jan 2004

Moore Jessica L, Gestl Erin E, Cheng Keith C

Abstract excerpt

We now know that genomic instability contributes to cancer. The zebrafish mosaic eye assay developed by George Streisinger takes advantage of the organism's transparency to provide an excellent assay for detecting somatic mutation. This assay allowed us to identify zebrafish mutants with increased frequencies of somatic mutation and spontaneous cancer. Here, we have described details of mutagenesis, the basis and...

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PMID: 15602892
DOI: 10.1016/s0091-679x(04)76025-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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