Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Tennessee Mouse Genome Consortium: identification of ocular mutants.

Visual neuroscience - 1 Jan 2000

Jablonski Monica M, Wang Xiaofei, Lu Lu, Miller Darla R, Rinchik Eugene M, Williams Robert W, Goldowitz Daniel

Abstract excerpt

The Tennessee Mouse Genome Consortium (TMGC) is in its fifth year of a ethylnitrosourea (ENU)-based mutagenesis screen to detect recessive mutations that affect the eye and brain. Each pedigree is tested by various phenotyping domains including the eye, neurohistology, behavior, aging, ethanol, drug, social behavior, auditory, and epilepsy domains. The utilization of a highly efficient breeding protocol and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes
Share to Ethylnitrosourea
Share to Eye

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eye Abnormalities

Share to Eye Color

Share to Eye Diseases

Share to Mutagens

Share to Organ Size

Source

Identifiers

PMID: 16332270
DOI: 10.1017/S0952523805225087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Tennessee Mouse Genome Consortium: identification of ocular mutants.PMID 16332270Read ↗

Novel ENU-induced eye mutations in the mouse: models for human eye disease.Semantic proximity Read ↗

Mouse models of ocular diseasesSemantic proximity Read ↗

Identification of genes required for eye development by high-throughput screening of mouse knockoutsSemantic proximity Read ↗

Results from screening over 9000 mutation-bearing mice for defects in the electroretinogram and appearance of the fundus.Semantic proximity Read ↗

ENU mutagenesis, a way forward to understand gene function.Semantic proximity Read ↗

Mutagenesis strategies for identifying novel loci associated with disease phenotypes.Semantic proximity Read ↗

Random mutagenesis of the mouse genome: a strategy for discovering gene function and the molecular basis of disease.Semantic proximity Read ↗

Generating mouse models of retinal disease using ENU mutagenesis.Semantic proximity Read ↗

Features and strategies of ENU mouse mutagenesis.Semantic proximity Read ↗

Saturation mutagenesis for dominant eye morphological defects in the mouse Mus musculus.Semantic proximity Read ↗

Mouse ENU mutagenesis.Semantic proximity Read ↗

Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.