Article
Linkage disequilibrium and haplotype analysis of two single nucleotide polymorphisms in STK15 in Chinese.
Yi chuan xue bao = Acta genetica Sinica - 1 Apr 2005
Chen Li, Ao Xue, Ren Qun, Wang Zhen-Ning, Lu Chong, Xu Yan, Jiang Li, Luo Yang, Xu Hui-Mian, Zhang Xue
Abstract excerpt
STK15 (Serine/Threonine protein kinase 15) is a serine/threonine kinase encoding gene, whose overexpression in mammalian cells leads to centrosome amplification, chromosomal instability, and oncogenic transformation. 91A-->T, a single nucleotide polymorphism (SNP) in exon 3 of STK15, has recently been shown to be associated with human cancer susceptibility. Within exon 3 of STK15, there are three nonsynonymous...
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