Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic anchoring of gene expression changes during estrogen-induced uterine growth.

Environmental health perspectives - 1 Nov 2004

Moggs Jonathan G, Tinwell Helen, Spurway Tracey, Chang Hur-Song, Pate Ian, Lim Fei Ling, Moore David J, Soames Anthony, Stuckey Ruth, Currie Richard, Zhu Tong, Kimber Ian, Ashby John, Orphanides George

Abstract excerpt

A major challenge in the emerging field of toxicogenomics is to define the relationships between chemically induced changes in gene expression and alterations in conventional toxicologic parameters such as clinical chemistry and histopathology. We have explored these relationships in detail using the rodent uterotrophic assay as a model system. Gene expression levels, uterine weights, and histologic parameters...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Primers
Share to Estradiol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Injections, Subcutaneous

Share to Mice, Inbred Strains

Share to Organ Size

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Uterus

Source

Open in PubMed Open full text

Identifiers

PMID: 15598610
DOI: 10.1289/txg.7345
PMCID: PMC1247656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic anchoring of gene expression changes during estrogen-induced uterine growth.PMID 15598610Read ↗

Uterine temporal response to acute exposure to 17alpha-ethinyl estradiol in the immature rat.Semantic proximity Read ↗

Information-dependent Enrichment Analysis Reveals Time-dependent Transcriptional Regulation of the Estrogen Pathway of ToxicitySemantic proximity Read ↗

Estrogen receptor phenotypes defined by gene expression profiling.Semantic proximity Read ↗

Mapping molecular responses to xenoestrogens through Gene Ontology and pathway analysis of toxicogenomic data.Semantic proximity Read ↗

Developmental exposure to diethylstilbestrol alters uterine gene expression that may be associated with uterine neoplasia later in lifeSemantic proximity Read ↗

Gene expression, dose-response, and phenotypic anchoring: applications for toxicogenomics in risk assessment.Semantic proximity Read ↗

Genetic control of ductal morphology, estrogen-induced ductal growth, and gene expression in female mouse mammary gland.Semantic proximity Read ↗

Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollution.Semantic proximity Read ↗

Long-term alteration of gene expression without morphological change in testis after neonatal exposure to genistein in mice: toxicogenomic analysis using cDNA microarraySemantic proximity Read ↗

Environmental Estrogens Differentially Engage the Histone Methyltransferase EZH2 to Increase Risk of Uterine TumorigenesisSemantic proximity Read ↗

Distinct estrogenic transcription programs of estetrol and estradiol across mammary, uterine, and vaginal cell types of pseudomenopaused miceSemantic proximity Read ↗

Association of cellular and molecular responses in the rat mammary gland to 17β-estradiol with susceptibility to mammary cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.