Article
Mapping molecular responses to xenoestrogens through Gene Ontology and pathway analysis of toxicogenomic data.
Reproductive toxicology (Elmsford, N.Y.) - 1 Jan 2000
Currie Richard A, Orphanides George, Moggs Jonathan G
Abstract excerpt
The recent sequencing of mammalian genomes has driven the development of genomic technologies, including microarray-based gene expression profiling, that allow simultaneous measurement of the expression levels of thousands of genes. Gene expression profiling applied to toxicology (toxicogenomics) has the potential to reveal, holistically, the molecular pathways and cellular processes that mediate the adverse...
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