Article
Uterine temporal response to acute exposure to 17alpha-ethinyl estradiol in the immature rat.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Jun 2007
Naciff Jorge M, Overmann Gary J, Torontali Suzanne M, Carr Gregory J, Khambatta Zubin S, Tiesman Jay P, Richardson Brian D, Daston George P
Abstract excerpt
The rat uterus responds to acute estrogen treatment with a series of well-characterized physiological responses; however, the gene expression changes required to elicit these responses have not been fully characterized. In order to understand early events induced by estrogen exposure in vivo, we evaluated the temporal gene expression in the uterus of the immature rat after a single dose of 17 alpha-ethinyl...
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