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Article

Exonic polymorphism vs intronic simple repeat hypervariability in MHC-DRB genes.

Immunogenetics - 1 Jan 1992

Ammer H, Schwaiger F W, Kammerbauer C, Gomolka M, Arriens A, Lazary S, Epplen J T

Abstract excerpt

Gene products encoded by the major histocompatibility complex often exhibit a high degree of polymorphism. In humans the HLA-DR polymorphism is due to more than 50 alleles with varying exon 2 sequences. Each group of DRB alleles contains a certain form of the basic simple repeat motif (gt)n(ga)m in intron 2. Identical alleles can be differentiated on the basis of the hypervariable repeat. In this study focused on...

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Identifiers

PMID: 1559718
DOI: 10.1007/BF00189896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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