Evolution of MHC polymorphism: extensive sharing of polymorphic sequence motifs between human and bovine DRB alleles.

doi:10.1007/BF01719239

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Article

Evolution of MHC polymorphism: extensive sharing of polymorphic sequence motifs between human and bovine DRB alleles.

Immunogenetics - 1 Jan 1991

Andersson L, Sigurdardóttir S, Borsch C, Gustafsson K

Abstract excerpt

The evolution of MHC polymorphism has been studied by comparing the amino acid and nucleotide sequences of 14 bovine and 32 human DRB alleles. The comparison revealed an extensive sharing of polymorphic sequence motifs in the two species. Almost identical sets of residues were found at several hi...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Biological Evolution
Cattle
HLA-DR Antigens
Humans
Molecular Sequence Data
Polymorphism, Genetic

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