Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of IL4, IL13, and ADRB2 genes in COPD.

Chest - 1 Dec 2004

Hegab Ahmed E, Sakamoto Tohru, Saitoh Wataru, Massoud Hosam H, Massoud Hosny M, Hassanein Khalid M, Sekizawa Kiyohisa

Abstract excerpt

STUDY OBJECTIVES: Interleukin (IL)-4, IL-13, and beta(2)-adrenoceptor (ADRB2) are involved in airway hyperresponsiveness (AHR), and their coding genes are located on chromosome 5q31-q33. AHR is one of the risk factors for COPD. Investigating polymorphisms within these genes may help to pinpoint the genetic susceptibility to COPD. SUBJECTS AND MEASUREMENTS: A case-control association study was conducted on two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 5
Share to Egypt
Share to Forced Expiratory Volume

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-13

Share to Interleukin-4

Share to Minisatellite Repeats

Share to Pulmonary Disease, Chronic Obstructive

Share to Receptors, Adrenergic, beta-2

Source

Identifiers

PMID: 15596681
DOI: 10.1378/chest.126.6.1832

Genes

ADRB2
AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of IL4, IL13, and ADRB2 genes in COPD.PMID 15596681Read ↗

Beta2-adrenergic receptor gene haplotypes and bronchodilator response in Egyptian patients with chronic obstructive pulmonary disease.Semantic proximity Read ↗

Interleukin-13 -1112 C/T promoter polymorphism confers risk for COPD: a meta-analysis.Semantic proximity Read ↗

Association Between ADRB2 Genetic Polymorphisms and the Risk of Chronic Obstructive Pulmonary Disease: A Case-Control Study in a Chinese Population.Semantic proximity Read ↗

Role of Genetic Polymorphisms in IL12Rβ2 in Chronic Obstructive Pulmonary Disease.Semantic proximity Read ↗

Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease.Semantic proximity Read ↗

SMAD4 rs10502913 is Significantly Associated with Chronic Obstructive Pulmonary Disease in a Chinese Han Population: A Case-Control Study.Semantic proximity Read ↗

Variants of the ADRB2 Gene in COPD: Systematic Review and Meta-Analyses of Disease Risk and Treatment Response.Semantic proximity Read ↗

Association of IL4RA polymorphism in predicting susceptibility toward chronic obstructive pulmonary disease.Semantic proximity Read ↗

Effect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: a prespecified substudy of the POET-COPD trial.Semantic proximity Read ↗

Genetic variants in FAM13A and IREB2 are associated with the susceptibility to COPD in a Chinese rural population: a case-control study.Semantic proximity Read ↗

RARB genetic variants might contribute to the risk of chronic obstructive pulmonary disease based on a case-control study.Semantic proximity Read ↗

Impact of IL13 genetic polymorphisms on COPD susceptibility in the Chinese Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.