Article
Impact of IL13 genetic polymorphisms on COPD susceptibility in the Chinese Han population.
Respiratory medicine - 1 Feb 2025
Yang Zehua, Zheng Yamei, Zhao Jie, Zhong Yi, Zhang Lei, Wu Haihong, Xie Tian, Ding Yipeng
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation. Interleukin-13 (IL13), associated with T-helper type 2 cells, plays a crucial role in COPD pathophysiology. This study aimed to investigate the relationship of single nucleotide polymorphisms (SNPs) in IL13 to COPD risk. METHODS: Five candidate SNPs of IL13 were genotyped using...
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