Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease.

doi:10.1111/j.1398-9995.2009.02167.x

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Article

Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease.

Allergy - 1 Apr 2010

Beghé B, Hall I P, Parker S G, Moffatt M F, Wardlaw A, Connolly M J, Fabbri L M, Ruse C, Sayers I

Abstract excerpt

BACKGROUND: Asthma and chronic obstructive pulmonary disease (COPD) are chronic respiratory diseases involving an interaction between genetic and environmental factors. Interleukin-13 (IL13) has been suggested to have a role in both asthma and COPD. We investigated whether single nucleotide polymorphisms (SNPs) in the IL13 pathway may contribute to the susceptibility and severity of asthma and COPD in adults....

Topics

Adult
Aged
Asthma
Female
Genetic Predisposition to Disease
Genotype
Haplotypes
Humans
Interleukin-13
Male
Middle Aged
Polymorphism, Single Nucleotide
Pulmonary Disease, Chronic Obstructive

Source

Open in PubMed

Identifiers

PMID: 19796199
DOI: 10.1111/j.1398-9995.2009.02167.x

Genes

FEV
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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