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Article

Interleukin-13 -1112 C/T promoter polymorphism confers risk for COPD: a meta-analysis.

PloS one - 1 Jan 2013

Chen Lei, Shen Yongchun, Liu Lian, Li Xiaoou, Wang Tao, Wen Fuqiang

Abstract excerpt

BACKGROUND: Interleukin (IL)-13, a T-helper type 2 cytokine, plays a critical role in the development of chronic obstructive pulmonary disease (COPD). This meta-analysis was performed to assess the association of IL-13 -1112 C/T promoter polymorphism with COPD susceptibility. METHODS: Published case-control studies from Pubmed and China National Knowledge Infrastructure (CNKI) databases were retrieved. Data were...

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PMID: 23874547
DOI: 10.1371/journal.pone.0068222
PMCID: PMC3706578

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