Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: a prespecified substudy of the POET-COPD trial.

The Lancet. Respiratory medicine - 1 Jan 2014

Rabe Klaus F, Fabbri Leonardo M, Israel Elliot, Kögler Harald, Riemann Kathrin, Schmidt Hendrik, Glaab Thomas, Vogelmeier Claus F

Abstract excerpt

BACKGROUND: The effect of β2-adrenergic receptor (ADRB2) polymorphisms on the treatment response to longacting bronchodilators in chronic obstructive pulmonary disease (COPD) is unclear. We aimed to establish whether ADRB2 polymorphisms differentially affected COPD exacerbation outcomes in response to tiotropium versus salmeterol. METHODS: We did a prespecified analysis of the ADRB2 polymorphisms Arg16Gly and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Albuterol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bronchodilator Agents

Share to Double-Blind Method

Share to Forced Expiratory Volume

Share to Pulmonary Disease, Chronic Obstructive

Share to Receptors, Adrenergic, beta-2

Share to Vital Capacity

Source

Identifiers

PMID: 24461901
DOI: 10.1016/S2213-2600(13)70248-0

Genes

ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: a prespecified substudy of the POET-COPD trial.PMID 24461901Read ↗

β2-Adrenergic Receptor (ADRB2) Gene Polymorphisms and Risk of COPD Exacerbations: The Rotterdam StudySemantic proximity Read ↗

Variants of the ADRB2 Gene in COPD: Systematic Review and Meta-Analyses of Disease Risk and Treatment Response.Semantic proximity Read ↗

Beta2-adrenergic receptor gene haplotypes and bronchodilator response in Egyptian patients with chronic obstructive pulmonary disease.Semantic proximity Read ↗

Effect of ADRB2 polymorphisms on response to longacting beta2-agonist therapy: a pharmacogenetic analysis of two randomised studies.Semantic proximity Read ↗

Effect of rare variants in ADRB2 on risk of severe exacerbations and symptom control during longacting β agonist treatment in a multiethnic asthma population: a genetic study.Semantic proximity Read ↗

Do genetic polymorphisms alter patient response to inhaled bronchodilators?Semantic proximity Read ↗

Effect of polymorphisms in the β2-adrenergic receptor on the susceptibility and pulmonary function of patients with chronic obstructive pulmonary disease: a meta analysis.Semantic proximity Read ↗

Beta2-adrenoceptor polymorphisms and obstructive airway diseases: important issues of study design.Semantic proximity Read ↗

Beta2-adrenergic receptor genetic polymorphisms and short-term bronchodilator responses in patients with COPD.Semantic proximity Read ↗

Beta-2-adrenoreceptor polymorphism at position 16 determines the clinical severity of chronic obstructive pulmonary disease.Semantic proximity Read ↗

Pharmacogenetics of chronic obstructive pulmonary disease: challenges and opportunities.Semantic proximity Read ↗

Pharmacogenetics of chronic obstructive pulmonary disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.