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Article

Tobacco use and increased colorectal cancer risk in patients with hereditary nonpolyposis colorectal cancer (Lynch syndrome).

Archives of internal medicine - 1 Jan 2000

Watson Patrice, Ashwathnarayan Ramesh, Lynch Henry T, Roy Hemant K

Abstract excerpt

BACKGROUND: The marked variability in age at onset of colorectal cancer (CRC) in patients with hereditary nonpolyposis colorectal cancer (HNPCC) makes management decisions difficult. Environmental factors governing the phenotypic variability of cancer-associated syndromes such as HNPCC have not been elucidated. METHODS: We determined whether tobacco use would alter CRC risk in carriers of HNPCC-associated...

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Identifiers

PMID: 15596632
DOI: 10.1001/archinte.164.22.2429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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