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Article

The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer.

Gastroenterology - 1 Oct 2001

Samowitz W S, Curtin K, Lin H H, Robertson M A, Schaffer D, Nichols M, Gruenthal K, Leppert M F, Slattery M L

Abstract excerpt

BACKGROUND & AIMS: Estimates of the frequency of hereditary nonpolyposis colon cancer (HNPCC) based on clinical criteria have varied widely. Recent studies of germline mismatch repair gene mutations have suggested that HNPCC accounts for close to 3% of all colon cancer, but this estimate may have been inflated by inclusion of founder effects peculiar to Finland. We therefore determined by genetic criteria the...

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Identifiers

PMID: 11606497
DOI: 10.1053/gast.2001.27996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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