Article
A surface phospholipase is involved in the migration of plasmodium sporozoites through cells.
The Journal of biological chemistry - 25 Feb 2005
Bhanot Purnima, Schauer Kristine, Coppens Isabelle, Nussenzweig Victor
Abstract excerpt
Plasmodium sporozoites, injected by mosquitoes into the skin of the host, traverse cells during their migration to hepatocytes where they continue their life cycle. The mechanisms used by the parasite to rupture the plasma membrane of the host cells are not known. Here we report the presence of a phospholipase on the surface of Plasmodium berghei sporozoites (P. berghei phospholipase; Pb PL) and demonstrate that...
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