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Article

Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage.

PloS one - 1 Jan 2018

Deligianni Elena, Silmon de Monerri Natalie C, McMillan Paul J, Bertuccini Lucia, Superti Fabiana, Manola Maria, Spanos Lefteris, Louis Christos, Blackman Michael J, Tilley Leann, Siden-Kiamos Inga

Abstract excerpt

Pore forming proteins such as those belonging to the membrane attack/perforin (MACPF) family have important functions in many organisms. Of the five MACPF proteins found in Plasmodium parasites, three have functions in cell passage and one in host cell egress. Here we report an analysis of the perforin-like protein 4, PPLP4, in the rodent parasite Plasmodium berghei. We found that the protein is expressed only in...

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Identifiers

PMID: 30102727
DOI: 10.1371/journal.pone.0201651
PMCID: PMC6089593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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