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Article

Role of a patatin-like phospholipase in Plasmodium falciparum gametogenesis and malaria transmission

14 Aug 2019

Abstract excerpt

Significance Malaria transmission involves a complex process that is initiated when Plasmodium gametocytes ingested during a blood meal are activated in the mosquito midgut and transform into gametes. The process of gametogenesis involves rounding up of activated gametocytes, exflagellation of male gametes, and gamete egress. Here, we have used a genetic approach to identify a patatin-like phospholipase,...

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Identifiers

PMID: 31413195
DOI: 10.1073/pnas.1900266116

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