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Article

Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex.

Current biology : CB - 14 Dec 2004

Lobachev Kirill, Vitriol Eric, Stemple Jennifer, Resnick Michael A, Bloom Kerry

Abstract excerpt

Chromosome aberrations are common outcomes of exposure to DNA-damaging agents or altered replication events and are associated with various diseases and a variety of carcinomas, including leukemias, lymphomas, sarcomas, and epithelial tumors. The incidence of aberrations can be greatly increased as a result of defects in DNA repair pathways. Although there is considerable information about the molecular events...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15589152
DOI: 10.1016/j.cub.2004.11.051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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